The movie opens with various news T.V. programs giving details pertaining to an incident occurring in Raccoon City, a made up (by Capcom) city set in the U.S., where a viral outbreak causes certain elected officials to send a nuclear missile to destroy the city. Another broadcast says that a pharmaceutical company, WilPharma, has planned to set up a new research facility in a (presumably) made up town called Havardville. We then cut to Havardville Airport, with planes taking off and landing. The film introduces us to Claire Redfield, who greets Rani and Rani's Aunt. Aunt goes to get the car, and Claire and Rani await her in the lobby. A man with gray hair and a Brittish accent comments on American humor. We cut to Senator Ron Davis, dodging news questions and then ordering the police to clear the Terra-Save members from the airport so he can leave. As he heads to the door, a man in a zombie-like mask is arrested for harassing the Senator, and while he is being cuffed, a man shambles into the picture. Unbeknownst to the poor Security Guard who is arresting the protester, this shambler is the first zombie in Resident Evil: Degeneration. [...]